Liver transplantation or hepatic transplantation is a surgical procedure performed when the liver fails to perform its normal functions such as synthesis of carbohydrates, proteins and fats. The liver is the second most commonly transplanted major organ, after the kidney, so it is clear that liver disease is a common and serious problem. Most liver transplant operations use livers from deceased donors, though a liver may also come from another living person (allograft). There is a significant proportion of demand liver transplantation currently in demand however, only the critically ill patients are given the priority and selection is based on the criticality of requirement.

There are several disease conditions responsible for liver transplantations such as:

• Liver Cirrhosis
• Cystic Fibrosis
• Hemochromatosis
• Primary biliary cirrhosis
• Primary sclerosing cholangitis
• Wilson’s disease

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Liver transplantation has also been associated with several risk factors such as bleeding, blood clots, anaphylactic reaction, and infection. Other risk factors such as osteopenia, diabetes, high blood pressure, high cholesterol and diarrhea are also observed post transplantation. According to the American Liver Foundation every year more than 1,500 people die waiting for a donated liver to become available. However, organ transplantation has also been life saving for thousands of people. It has been studied that almost 6,000 liver transplants are performed annually in the U.S. and this number continues to grow. Currently in the U.S. alone there are almost 17,000 adults and children who have been approved for liver transplantation and are awaiting for the donors to make livers available.

Liver Transplantation Market: Drivers and Restraints

Liver Transplantation market is growing rapidly due to increasing incidence of Hepatitis A, B and C across the globe. Major drivers for the liver transplantation market are treatment advancements, increasing adoption as the most effective modality for the management of end-stage liver disease. Furthermore, increasing favored reimbursement policies is expected to drive the growth of the liver transplantation market in the near future. However adequate number of liver donors, increasing waiting list to get a new liver and length of hospital stay and its cost are the major factors that can hamper the Liver Transplantation market growth over the forecast period.

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Liver Transplantation Market: Segmentation

The global liver transplantation market is classified on the basis of treatment type, end use and geography.

Based on treatment type, global liver transplantation market is segmented into the following:

• Liver Transplantation Surgery
• Post-Surgery Anti-Rejection Treatment
• Cyclosporine
• Tacrolimus
• Sirolimus
• Prednisone
• Azathioprine
• Mycophenolate Mofetil

Based on end use, global liver transplantation market is segmented into the following:

• Hospitals
• Adult Liver Transplantation Centers
• Ambulatory Surgical Centers

Liver Transplantation Market: Overview

Liver Transplantation market is growing with a significant CAGR due to its high adoption rate as it is an effective modality for the management of end-stage liver disease. Developing countries are growing with a slower CAGR compared to other parts of the world. By end use, hospitals and adult liver transplantation centers segments are expected to account for around 50% share in the global liver transplantation market and the trend is forecast to continue through 2026. Based on treatment type, liver transplantation surgery is expected to register above average CAGR over the forecast period owing surgical techniques and innovations in living related liver transplantations.

Liver Transplantation Market: Region-wise Outlook

Depending on geographic region, global liver transplantation market is segmented into seven key regions: North America, South America, Eastern Europe, Western Europe, Asia Pacific Excluding Japan, Japan, and Middle East & Africa. North America leads the market for liver transplantation followed by the European countries. Since, the availability of liver donors is scarce, the market is not yet well established in the developing markets such as India, China and others.

Market: Key Players

Key players in the Liver Transplantation Market include Allosource, Conatus Pharmaceuticals Inc., Digna Biotech, S.L., Dompe Farmaceutici S.p.A., Isogenis, Inc., RedHill Biopharma Ltd., Thompson Surgical, Integra Life sciences and others.